Quick Answer

An anti-cheat error in Honkai: Star Rail on the GeForce RTX 5060 is a permissions and security conflict, not a graphics fault. Launch the HoYoPlay client as administrator, allow the anti-cheat service through Windows Security, and disable any conflicting overlay or memory-tuning tool — that clears it in most cases. Hardware tier (whether a entry-mid card or a handheld) has nothing to do with the error.

Fix the anti-cheat conflict step by step

On the GeForce RTX 5060, right-click the launcher and Run as administrator so the anti-cheat driver can load with the rights it needs. Add the game's install folder to the Windows Security exclusion list, and pause any third-party antivirus for one launch. Close MSI Afterburner, RivaTuner, Discord overlay and similar hooks — these are the most common triggers for the 'anti-cheat failed to initialise' message.

Driver and Windows checks on the GeForce RTX 5060

Reinstall the latest driver for the GeForce RTX 5060 through the NVIDIA App (or GeForce control panel) using the clean-install option; a partial driver after an update can break the anti-cheat handshake. If Windows has Hyper-V or Memory Integrity (Core Isolation) enabled, the kernel-level anti-cheat sometimes refuses to start — toggle Memory Integrity off, reboot, and test. A entry-mid GPU around R8,500 at Evetech is never the cause; the fix lives entirely in Windows and the launcher.

Stop the error coming back

Remove any fps-unlock, FOV or memory-edit mods — these are flagged by the anti-cheat and will re-trigger the error every patch. Keep the HoYoPlay client updated, and re-add the exclusion after a major Windows feature update, since those occasionally reset Security settings. Evetech stocks the matching driver-friendly cards and handhelds locally if you do decide to upgrade for other reasons.

FAQ

Why does Honkai: Star Rail show an anti-cheat error only on the GeForce RTX 5060?

It isn't actually the the GeForce RTX 5060 causing it — the error follows your Windows security and overlay setup, which happens to be on this machine. Running the launcher as administrator and whitelisting it usually clears the message immediately.

Does Core Isolation / Memory Integrity break the anti-cheat?

It can. Windows Memory Integrity sometimes blocks kernel-level anti-cheat from loading. Turn it off in Windows Security under Device Security, reboot, and test the launch again.

Will reinstalling the game fix the anti-cheat error?

Often, but try the lighter fixes first. Run as administrator, add a Security exclusion and remove mods before a full reinstall, since those resolve the error far faster on the GeForce RTX 5060.

Run HoYoPlay as administrator, add the game folder to Windows Security exclusions, and disable Memory Integrity — that trio fixes the anti-cheat error on the GeForce RTX 5060 without an upgrade.